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DNA adducts-chemical addons

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Jan 2015 English Publisher:MedknowJournal:Journal of Pharmacy And Bioallied Sciences, volume 7, page 197 (issn: 0975-7406,

Authors: T R Rajalakshmi; K. M. K. Masthan; K T Shanmugam; N AravindhaBabu;

doi: 10.4103/0975-7406.155901

pmid: 26015708

pmc: PMC4439668

DNA adducts-chemical addons

- Summary
- Subjects
- Metrics

Abstract

DNA adduct is a piece of DNA covalently bond to a chemical (safrole, benzopyrenediol epoxide, acetaldehyde). This process could be the start of a cancerous cell. When a chemical binds to DNA, it gets damaged resulting in abnormal replication. This could be the start of a mutation and without proper DNA repair, this can lead to cancer. It is this chemical that binds with the DNA is our prime area of concern. Instead of performing the whole body analysis for diagnosing cancer, this test could be carried out for early detection of cancer. When scanning tunneling microscope is used, the DNA results can be obtained earlier. DNA adducts in scientific experiments are used as biomarkers.

Related Organizations

Sree Balaji Dental College and Hospital
India

Keywords

QD71-142, DNA adducts, DNA repair, Biomarker, RS1-441, Pharmacy and materia medica, scanning tunneling microscope, Dental Science - Review Article, Analytical chemistry

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	21
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average