An Xpert screen to identify carbapenemases
Copyright policy )An Xpert screen to identify carbapenemases
To prevent the spread of carbapenemases-producing Enterobacteriaceae (CPE) active surveillance, contact isolation and cohorting infected patients should be practiced. Rectal swabs for the Xpert MDRO-assay of 32 patients were included. 71.85% were positive for targets incorporated into the MDRO-assay; whereas 28% were phenotypically not CRE and Xpert negative (9.37% had different mechanism [bla OXA]). The assay identified 59.3%, 9.37% and 3.1% as bla NDM, bla NDM+VIM and bla VIM, respectively. The assay is a screening test that identifies CPE harbouring organism within an hour and can be installed at tertiary-care facilities to screen colonized patients.
Bacteriological Techniques, Bacterial Proteins, Enterobacteriaceae, Enterobacteriaceae Infections, Rectum, Humans, Mass Screening, Multiplex Polymerase Chain Reaction, beta-Lactamases
Bacteriological Techniques, Bacterial Proteins, Enterobacteriaceae, Enterobacteriaceae Infections, Rectum, Humans, Mass Screening, Multiplex Polymerase Chain Reaction, beta-Lactamases
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