The corollary of the humanist project for human enhancement is transhumanism, which considers post-human modes of existence to be desirable, and aspires to overcome our vulnerability by incorporating available technology into our nature. One of its manifestations is the queer theory, which calls for actively redefining the “self”, starting with the sexed body and its functioning. This article analyses the transhumanist impulse and the queer theory from the concepts of emancipation and progress, asking the following questions: a) What do both terms mean when we refer to human beings? and b) Are transhumanism and the queer theory examples of true emancipation and progress, or conversely, a relapse into to our primitive state of nature that orders praxis to the subjugation of nature and the imperative of self-preservation?