mHealth is a very attractive field for mobile applications developers, but it also involves new challenges that developers of programs intended for standard desktops do not usually face. Hence, the first part of this chapter is devoted to survey the development platforms and languages utilized to develop the associated applications of the mHealth system. mHealth is a communications system that consists of mobile devices for collecting and delivering clinical health data to practitioners, researchers and patients. It is also a tool used in the real-time monitoring of patient vital signs, and direct provision of care. Therefore, the second part of this chapter will focuses on the survey of wireless technologies envisioned for use in the mHealth system.