This chapter addresses the issue of product development chain from the perspective of data modeling and streamlining. The focus is on an emerging ISO standard, informally known as STEP-NC, and how it may close the gap between design and manufacturing for a complete, integrated product development environment. This new standard defines a new generation of NC programming language and is fully compliant with STEP. There is a whole suite of implementation methods one may utilize for development purposes. STEP-NC brings richer information to the numerically-controlled machine tools; hence, intelligent machining and control are made possible. Its Web-enabled feature gives an additional dimension in that e-manufacturing can be readily supported. A case study toward the end demonstrates a STEP compliant, Web-enabled manufacturing system.