<abstract><p>In this work, we propose and investigate a predator-prey model where the prey population is structured by sex and the predators (unstructured) depredate based on sex-bias. We provide conditions for the existence of equilibrium points and perform local stability analysis on them. We derive global stability conditions for the extinction state. We show the possible occurrence of Hopf and saddle-node bifurcations. Multiple Hopf bifurcations are observed as the sex-biased predation rate is varied. This variation also shows the opposite consequences in the densities of the sex-structured prey. Our results show that sex-biased predation can cause both stabilizing and destabilizing effects for certain parameter choices. It can also cause an imbalanced sex-ratio, which has ecological consequences. Furthermore when intraspecific competition among predators is minimized, it can lead to the extinction of prey. We discuss the ecological implications and application of our results to the biocontrol of invasive species susceptible to sex-biased predation.</p></abstract>