Garsia and Remmel (JCT. A 41 (1986), 246-275) used rook configurations to give a combinatorial interpretation to the $q$-analogue of a formula of Frobenius relating the Stirling numbers of the second kind to the Eulerian polynomials. Later, Remmel and Wachs defined generalized $p,q$-Stirling numbers of the first and second kind in terms of rook placements. Additionally, they extended their definition to give a $p,q$-analogue of rook numbers for arbitrary Ferrers boards. In this paper, we use Remmel and Wach's definition and an extension of Garsia and Remmel's proof to give a combinatorial interpretation to a $p,q$-analogue of a formula of Frobenius relating the $p,q$-Stirling numbers of the second kind to the trivariate distribution of the descent number, major index, and comajor index over $S_n$. We further define a $p,q$-analogue of the hit numbers, and show analytically that for Ferrers boards, the $p,q$-hit numbers are polynomials in $(p,q)$ with nonnegative coefficients.