Using a sample of kindergarten caretakers, this study shows that knowledge about Hand food and mouth disease (HFMD) is considered to be moderate (62.0%). Questionnaires were attained from 197 caretakers from a range of kindergarten in Kuala Nerus district, via universal sampling. The study shows that, within the sample of Kuala Nerus caretakers, insufficient HFMD knowledge does not diverge between educational background and source of health information. The research also indicates that those with experience are more conversant workers. Electronic and social media are the most selected channel by the caretakers for obtaining knowledge. KEYWORDS:HFMD, Caretakers, Kindergarten, Source of Information.