Callicarpa macrophylla Vahl., species of Beautyberry, is used as both internally as well as externally for its several beneficial health effects. Our objective was to determine the antifungal activity of ethanolic(SEE) and aqueous(SAE) extracts of the stems of C. macrophylla Vahl. Agar disc diffusion method was adopted for the antifungal screening against seven fungal strains. The overall results provide promising baseline information for the potential use of the crude antifungal extracts from C. macrophylla in the treatment of fungal infection. Further isolation of the responsible phytoconstituents may lead this plant to reach the bed side. © 2011 IGJPS. All rights reserved.