The objective of this research work was to determine the factors of entrepreneurial culture in university students. The present study was designed with a quantitative approach of descriptive, non-experimental and cross-sectional scope, approached from a review of the literature and based on a theoretical and referential framework. This research work was carried out in the period February-June 2019, whose subjects of study were students of the Veracruzana University of the School of Accounting and Administration and the Technological University of Southeast Veracruz. Among the main findings, it was found that university students do not undertake due to lack of financial resources, they also consider that it is necessary to strengthen academic activities within higher education institutions that help them develop entrepreneurship and innovation skills. The main factors that determine the entrepreneurial culture are creativity, teamwork, initiative, fear of risk.