As a particular type of alpine glacier, debris-covered glaciers are essential for local water resources and glacial disaster warnings. The Eastern Tomur Peak Region (EPTR) is the most concentrated glacier in Tien Shan Mountain, China, where the glaciers have not been studied in detail. This paper evaluates the delineation accuracy of Landsat8 OLI, Sentinel-1A, and GF images for debris-covered glaciers in the EPTR. Each image uses the most advanced delineation method for itself to minimize the error of inherent resolutions. The results show that the accuracy of these images for delineating debris-covered glaciers is very high, and the F1 scores are expressed as 96.73%, 93.55%, and 95.81%, respectively. Therefore, Landsat images were selected to analyze the area change of EPTR from 2000 to 2022 over a 5-year time scale. The results indicate that glaciers of the EPTR decreased by 19.05 km2 from 2000 to 2020, accounting for 1.9% (0.08% a−1), and debris increased by 10.8%, which validates the opinion that the presence of debris inhibits glacier melting. The most varied time was 2010–2022, but it was much less than other Tien Shan regions. The lower glacier ablation rate in this area results from the combined effect of decreased bare ice and increased debris. The main reason for the change in debris-covered glaciers is the increase in temperature.