In this article, the integral transform is used to introduce a new family of extended hybrid Sheffer sequences via generating functions and operational rules. The determinant forms and other properties of these sequences are established using a matrix approach. The corresponding results for the extended hybrid Appell sequences are also obtained. Certain examples in terms of the members of the extended hybrid Sheffer and Appell sequences are framed. By employing operational rules, the identities involving the Lah, Stirling and Pascal matrices are derived for the aforementioned sequences.