We primarily investigate the existence of solutions for fractional neutral integro-differential equations with nonlocal initial conditions, which are crucial for understanding natural phenomena. Taking into account factors such as neutral type, fractional-order integrals, and fractional-order derivatives, we employ probability density functions, Laplace transforms, and resolvent operators to formulate a well-defined concept of a mild solution for the specified equation. Following this, by using fixed-point theorems, we establish the existence of mild solutions under more relaxed conditions.