Cultural history of nanominiaturization, computing, quantum computing and simulating is necessary to comprehend human character and place it in the whole of living beings. Ideas in the history of physics by Feynman, etc. are valued by the questions that generate. A series of questions, answers and hypothesis introduces the nature of the history of nanominiaturization, providing facts. Nanotechnology adds a third dimension to the periodic table of the elements. Thinking about computers was useful. It must do with learning computers possibilities and physics potential. Provisional conclusions follow. (1) Nature (space–time) is not classical but discrete; quantization is a different kind of mathematics. (2) Nanomaterials differ from conventional ones because of large surface-to-volume ratios and quantum effects. (3) Feynman predicted: (a) in the nanoworld, one has a lot of things that would happen that represent opportunities for design; (b) other way to simulate the probabilistic nature is by a computer, which itself be probabilistic. (4) Problems are temperature and isolation. (5) Advances exist in low-temperature materials and high-energy physics; promises, in superconductivity. (6) Computing possibilities tell people about computer rules and physics. (7) Philosophers work better if they are interested in the data that scientists unveil. (8) Researchers should not be afraid to transcend cultural boundaries in search for the truth.