Antigen-Presenting Cells and Antigen Presentation in Tertiary Lymphoid Organs
Copyright policy )Antigen-Presenting Cells and Antigen Presentation in Tertiary Lymphoid Organs
Tertiary lymphoid organs (TLOs) form in territorialized niches of peripheral tissues characterized by the presence of antigens; however, little is known about mechanism(s) of antigen handling by ectopic lymphoid structures. In this mini review, we will discuss the role of antigen-presenting cells and mechanisms of antigen presentation in TLOs, summarizing what is currently known about this facet of the formation and function of these tissues as well as identifying questions yet to be addressed.
- Queen Mary University of London United Kingdom
- University of Glasgow United Kingdom
- University of Edinburgh United Kingdom
- University of Perugia Italy
- Medical Research Council United Kingdom
tertiary lymphoid organs, Antigen Presentation, B cells, Macrophages, follicular dendritic cells, Immunology, Dendritic Cells, antigen presenting cells, RC581-607, macrophages, antigen presentation, B cells; antigen presentation; antigen-presenting cells; dendritic cells; follicular dendritic cells; macrophages; tertiary lymphoid organs, antigen-presenting cells, dendritic cells, Immunologic diseases. Allergy, Follicular dendritic cells
tertiary lymphoid organs, Antigen Presentation, B cells, Macrophages, follicular dendritic cells, Immunology, Dendritic Cells, antigen presenting cells, RC581-607, macrophages, antigen presentation, B cells; antigen presentation; antigen-presenting cells; dendritic cells; follicular dendritic cells; macrophages; tertiary lymphoid organs, antigen-presenting cells, dendritic cells, Immunologic diseases. Allergy, Follicular dendritic cells
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