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Heart Failure With Mid-range Ejection Fraction: Every Coin Has Two Sides

descriptionPublicationkeyboard_double_arrow_right Article 21 Jul 2021Publisher:Frontiers Media SAJournal:Frontiers in Cardiovascular Medicine, volume 8 (eissn: 2297-055X, Copyright policy )
Authors: Kaiyuan Zhu; Teng Ma; Yang Su; Xin Pan; Rongrong Huang; Fenglei Zhang; Chunxi Yan; +2 Authors

doi: 10.3389/fcvm.2021.683418

pmid: 34368245

pmc: PMC8333279

Heart Failure With Mid-range Ejection Fraction: Every Coin Has Two Sides

Abstract

This review summarizes current knowledge regarding clinical epidemiology, pathophysiology, and prognosis for patients with HFmrEF in comparison to HFrEF and HFpEF. Although recommended treatments currently focus on aggressive management of comorbidities, we summarize potentially beneficial therapies that can delay the process of heart failure by blocking the pathophysiology mechanism. More studies are needed to further characterize HFmrEF and identify effective management strategies that can reduce cardiovascular morbidity and mortality of patients with HFmrEF.

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Keywords

heart failure with preserved ejection fraction, heart failure with mid-range ejection fraction, RC666-701, heart failure, Diseases of the circulatory (Cardiovascular) system, heart failure with reduced ejection fraction, Cardiovascular Medicine, left ventricular ejecting fraction

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    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 9
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
9
Top 10%
Average
Top 10%
Green
gold
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