The development of foreign economic activity of the enterprise is the primary task of any enterprise in order to achieve recognition on the world stage and interest in cooperation with foreign partners. The article examines the theoretical foundations and developed a system of recommendations for increasing the efficiency of management of the enterprise's foreign economic activity. The research methodology consists in considering a set of factors affecting the comprehensive assessment of the effectiveness of the management of the enterprise's foreign economic activity. The aspects of managing the foreign economic activity of the enterprise and increasing its efficiency with the help of induction and deduction methods, the synthesis method were studied, the concept of foreign economic activity was generalized, and the existing approaches and directions for increasing the efficiency of the enterprise's foreign economic activity were studied. The article proves the necessity of using modern information systems for the formation and effective management of foreign economic activities of enterprises. The scientific novelty and theoretical significance of the obtained results lies in the fact that, on the basis of the conducted research, a comprehensive approach to the management of the foreign economic activity of the enterprise is proposed, the use of which will allow to evaluate the efficiency of the enterprise.