Wind-induced vibration coefficient β is an essential parameter for the structural wind-resistant design. In order to provide accurate design wind loads, β of a landscape tower with curved and twisted columns and spiral beams (short for LT) is studied by wind tunnel test and numerical simulation. The results show that the displacement wind-induced vibration coefficient is greatly affected by wind yaw angle. Moreover, the inertial load wind-induced vibration coefficients increase along the height and increase sharply at the platform position. Due to the influence of nonuniform shape and mass distribution and wind yaw angle, β calculated by the Chinese and American load code does not apply to LT structures. In addition, this article puts forward some suggestions for the shortcoming in the use of code to calculate β of LTs and made some prospects for future research on wind-resistant design of LTs, hoping to provide theoretical guidance and thinking inspiration for future research.