Orthopoxvirus DNA in Eurasian Lynx, Sweden
Copyright policy )Orthopoxvirus DNA in Eurasian Lynx, Sweden
Cowpox virus, which has been used to protect humans against smallpox but may cause severe disease in immunocompromised persons, has reemerged in humans, domestic cats, and other animal species in Europe. Orthopoxvirus (OPV) DNA was detected in tissues (lung, kidney, spleen) in 24 (9%) of 263 free-ranging Eurasian lynx (Lynx lynx) from Sweden. Thymidine kinase gene amplicon sequences (339 bp) from 21 lynx were all identical to those from cowpox virus isolated from a person in Norway and phylogenetically closer to monkeypox virus than to vaccinia virus and isolates from 2 persons with cowpox virus in Sweden. Prevalence was higher among animals from regions with dense, rather than rural, human populations. Lynx are probably exposed to OPV through predation on small mammal reservoir species. We conclude that OPV is widely distributed in Sweden and may represent a threat to humans. Further studies are needed to verify whether this lynx OPV is cowpox virus.
- The Arctic University of Norway Norway
- University of Bern Switzerland
- Norwegian University of Life Sciences Norway
Male, wildlife, Molecular Sequence Data, VDP::Medical disciplines: 700::Clinical medical disciplines: 750::Communicable diseases: 776, orthopoxvirus, Infectious and parasitic diseases, RC109-216, Orthopoxvirus, Poxviridae Infections, Thymidine Kinase, Viral Proteins, VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Infeksjonsmedisin: 776, VDP::Agriculture and fishery disciplines: 900, Animals, viruses, Cowpox virus, Phylogeny, Sweden, 630 Agriculture, Base Sequence, VDP::Landbruks- og Fiskerifag: 900, Research, R, zoonosis, DNA, Viral, Lynx, Medicine, epidemiology, Female, Sequence Alignment
Male, wildlife, Molecular Sequence Data, VDP::Medical disciplines: 700::Clinical medical disciplines: 750::Communicable diseases: 776, orthopoxvirus, Infectious and parasitic diseases, RC109-216, Orthopoxvirus, Poxviridae Infections, Thymidine Kinase, Viral Proteins, VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Infeksjonsmedisin: 776, VDP::Agriculture and fishery disciplines: 900, Animals, viruses, Cowpox virus, Phylogeny, Sweden, 630 Agriculture, Base Sequence, VDP::Landbruks- og Fiskerifag: 900, Research, R, zoonosis, DNA, Viral, Lynx, Medicine, epidemiology, Female, Sequence Alignment
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).15 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!