In the Brazilian Amazon region, cultural “mixture” is expressed in the interaction of city and hinterland, of Indigenous and Black, of religiosity and politics. By examining the multiple cultural and ethnic threads that traverse this landscape, The Amazonian Puzzle sets out to show how the category of caboclo (a powerful spiritual entity to some, and to others a despised peasant of mixed ancestry) reveals deep currents of ethnic recompositions, religious interpenetration, and social hierarchy. These Amazonian dynamics are explored through the lens of ethnography, sociology, and history.