This study presents a computational method to estimate a global damage index of a RC construction. The method is based on the evaluation of local damage combined with an analysis of the probable collapse mechanism of the structure. A constitutive model for reinforced concrete, including global damage variables for concrete and steel elasto-plastic models, is integrated in a multilayered finite element code. The locations of pseudo plastic hinges in a structure are obtained in the areas of maximal damage through simulation by the FE method. The global index is derived from a specific formula taking into account the damage recorded in the critical zones of the structure (pseudo plastic hinges) and the damage computed in the less damaged areas. The proposed method is validated on a RC frame structure application. The diagram "global index vs. loading" shows a specific shape and gives interesting results for the discussion of the possibility of reparation.