Numerous studies by Russian scientists and historians of science are devoted to the state science policy in the USSR and its well-known achievements, but not enough attention is paid to the negative, socially repressed aspects of the Soviet science policy. Repressions became one of the main components of the state's scientific and personnel policy in the Stalinist era. The systemic analysis of the development of Soviet science declared in the scientific literature, limited only by its indisputably outstanding achievements, without under-standing the origins, causes and mechanisms of the repressed state apparatus that operated in the same period, sharply reduces the overall picture of the reliability of the study of Soviet science. The purpose of the study is to comprehend the diverse and dramatic practice of state repression in the system of Soviet science, because in the world history of science no other developed country has experienced such large-scale and tragic events in the functioning of the scientific society.