This paper describes an innovative approach to teaching a traditional subject-physiology. There are no lectures, tutorials or practicals. All learning activities are undertaken in small groups, and the course is learner-centred and problem-orientated. Students are required to collect and record their own information and to teach their colleagues what they have learned. Peer evaluation by students is used. The great majority of students enjoy the course and find it valuable. However, the structure of the course is not yet regarded as optimal. It is suggested that the system should complement and supplement traditional methods, rather than replace them entirely.