The Activities of Extraction &lt;i&gt;Litsea &lt;/i&gt;sp Leaf Plant Against &lt;i&gt;Candida Albicans&lt;/i&gt;  and  &lt;i&gt;Trichophyton Rubrum&lt;/i&gt;

descriptionPublicationkeyboard_double_arrow_right Article 16 Apr 2010Publisher:Universitas PapuaJournal:Beccariana Botanical Research Bulletin, volume 7 (issn: 1410-5403,

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Authors: S. Y. Randa; Faizah Hamzah; Poniah Andayaningsih; - Supriyatna;

doi: 10.30862/bbrp.v7i2.264

The Activities of Extraction Litsea sp Leaf Plant Against Candida Albicans and Trichophyton Rubrum

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Abstract

A study to investigate the antifungal activity of soxhletion extract and maceration extract of the Litsea sp leaf plant against Candida albicans and Trichophyton rubrum has been done. Litsea sp plant is used for anti-inflammation. Extraction of Litsea sp leaf was conducted with soxhletation and maceration method using ethanol 70% solvent. The dilution tube method was used for detecting antifungal activity as concentration extract 40%; 30%; 20%; 10%; 5%; 2.5%; 125%; 0.625%; 0.3125%; 0.15625%; 0.078125; 0.0%. The results of this study indicated that soxhletion and maceration extract of Litsea sp leaf have antifungal activity against Candida albicans and Trichophyton rubrum. The minimal inhibiting concentration of soxhletion killing concentration of 5% against Candida albicans; whereas minimal inhibiting concentration at concentration of 1.25% against Trichophyton rubrum. The minimal inhibiting concentration and minimal killing concentration extract at concentration of 10% against Candida albicans, while minimal inhibiting concentration and minimal killing concentration at concentration of 2.5% against Trichophyton rubrum.

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