Tumors of the airway can be classified into malignant (squamous and adenoidcystic) and low-grade or benign neoplasms. The most common tumors are squamous cancer and adenoidcystic, occurring in about equal numbers. Pre- and intraoperative evaluations are mandatory, along with strict attention to technical details and postoperative care. Both squamous cancers and adenoidcystic cancers should be treated with postoperative irradiation. Successfully removed benign tumors do not require additional therapy and are almost always cured by resection and reconstruction.