Individuals rely on the spatial distance between a person and an object as a cue to draw inferences about the person’s expertise regarding the domain represented by this object. In three studies, I investigated the relationship between spatial distance and expertise. In a fourth study, I tested the hypothesis that spatial distance affects the persuasion process (total N = 532). Study 1 provided initial empirical evidence that the shorter the subjectively perceived distance between a target and an object, the higher participants rated the target’s expertise. Studies 2A and 2B demonstrated the causal relationship between spatial distance and expertise. Across different domains of expertise, targets spatially close to an object were attributed more expertise regarding the according domain compared to targets at a large spatial distance. Study 3 revealed that the link between spatial distance and expertise is bidirectional: Describing targets as experts in specific domains caused participants to actively place objects closer to targets whose expertise matched the according object. Study 4 indicated that spatial distance affects the attitude change process analogously to expertise cues known from persuasion research. A communicator spatially close to an object was more effective at changing participants’ attitudes toward the object than a spatially distant communicator. The findings of the present studies support the conclusion that individuals infer another person’s expertise in a certain domain from the respective person’s spatial distance to an object epitomizing the relevant domain. Moreover, the results illustrate the relevance of spatial distance for persuasion.