Summary: The purpose of this study therefore is to investigate the relationship between the head circumference and waist circumference of male and female subjects in Nigeria and also if there exists any significant difference in male and female head circumferences and waist circumferences. Materials and Methods: This descriptive cross-sectional study adopted the simple random sampling technique. The sample population comprised of male and female subjects in Nigeria, whose ages lie between 18-58years. A total of five hundred (500) subjects were screened and three hundred (300) were selected for this study. Data were collected with the aid of a measuring tape and a data sheet. Results: The highest mean ± standard deviation of head and waist circumference was recorded in females and there was a relationship between head and waist circumference [56.63±1.36mm and 73.03±7.59mm mm] respectively. Conclusion: The study therefore showed a significant variation in the studied parameters and thus, the correlation between the head circumference and waist circumference is useful in the analysis and classification of fossil remains, as well as the study of living population.