Use-wear analysis of lithic artefacts is based on macro and microscopic observation of traces (such as scaling, rounding, striation and polish) that appear on objects when they are manufactured and used. Results are interpreted in terms of cinematics and worked materials through analogic reasoning in reference to experimental and ethnoarchaeological corpus. Since the 80's, following the pioneering work of S.A. Sevenov, use-wear analysis was applied to Anatolian lithic assemblages. This paper presents an overview of the different approaches conducted. Goals are mainly to underline the link between stone production and human behaviors and to reconstruct of technological developments through time. The research aims to go beyond typology for instance re-interpreting 'cultural markers'. The chipped stone tools are, as well, contextualized, inserted into ancient activities related to subsistence or crafts. We approach human behaviors at ancient communities and data on the use of spaces within settlements are obtained. In Anatolia, studies were conducted mostly on early Neolithic contexts at a time in which agriculture and herding were incipient. In this context, documenting technical practices related to subsistence is essential. Furthermore, a multitude of activities showing different levels of specialization in craftsmanship were noted. These results illustrate the daily life and the regional cultural identities of Neolithic communities in Anatolia.