Severe livestock losses caused by tall larkspur (Delphinium spp.) consumption have caused many producers to try various preventative measures, including the use of mineral-salt supplementation. The objective of tbis study was to determine if additions or deletions of a mineral-salt supplement (Binn's #1 Alleviator) would alter the response (i.e., rate of nose pressing) of cattle to tall larkspur exposure. The dose response of 5 Jersey steers was examined by systematically adding 0.25 mg of mineral-salt/kg body weight, and comparing responses in the same steers without salt supplements. Steers were then run under a variable ratio (VR) reinforcement schedule and periodically dosed with tall larkspur at a level causing a significant decrease in responding without provoking overt signs of intoxication. Response rate with and without mineral-salt supplement was the major dependent variable; 3 to 5 "on-off" cycles were conducted for each subject. Steers reduced (P 0.1) grain intake (1.64 +/- 0.17 kg/session) compared to days when no mineral was given (1.76 +/- 0.13 kg/session). On larkspur dose days (i.e. when animals were intoxicated), the average response rates were 82.9 +/- 3.7 and 85.8 +/- 4.0 responses/min (P > 0.1) when off and on mineral, respectively. We concluded that mineral/salt supplementation had no effect on the response of steers to doses of tall larkspur that produced subclinical intoxication.