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Biometrics
Article . 1979 . Peer-reviewed
Data sources: Crossref
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A General Model for the Hazard Rate with Covariables

A general model for the hazard rate with covariables
Authors: Taulbee, John D.;

A General Model for the Hazard Rate with Covariables

Abstract

with the coeffiicients of the various powers of time being possibly diffierent functions of the vector of covariables. Methods for fitting the model to data and testing hypotheses about model parameters are presented. The degree of the polynomial for the hazard is chosen in a step-wise manner as part of thefitting of the model. Specification of the survival curve with covariables is straightforward as a result of the parametric nature of the model. [Jse of the model and methods forfitting and hypothesis testing are illustrated by application to two diffierent cohort studies. For each analysis, a single covariate indicates in which of two treatment groups an individual belongs. It is found that a time-constant hazard and hence, the proportional hazards assumption are adequate for thefirst cohort examined. However, for the second cohort a time-varying hazard is required and the proportional hazards assumption is not suitable. Results obtained using other methods are compared with those of the proposed method for both of the cohorts. Good agreement among the diffierent approaches is observed.

Keywords

hazard rate, Reliability and life testing, Point estimation, parametric model, Parametric hypothesis testing, Applications of statistics to biology and medical sciences; meta analysis, survival data, likelihood ratio clinical trials, cohort studies, covariables, model fitting, test of proportional hazard assumption

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
20
Top 10%
Top 1%
Average
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