Study of collections of Lisianthus L. from hitherto uncollected areas in Panama, viz. Cerro Jefe in the Province of Panama and the mouth of Rio Concepcion in the Province of Veraguas, yielded the following two new species: L. jefensis and L. scopulinus. During the December 1967 Missouri Botanical Garden's expedition to Panama under the direction of Walter H. Lewis (in which the senior author took part), collecting along the mouth of Rio Concepcion and in other inaccessible areas was made possible through a grant from the U.S. Air Force Office of Scientific Research (Grant No. F44620-67-C-0055). This included transportation by helicopter from Albrook Air Force Base in the Canal Zone to sites in the Provinces of Colon, Darien, Los Santos, Panama, Veraguas, and in the Comarca de San Blas.