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The Influence of Vitamin D on Neurodegeneration and Neurological Disorders: A Rationale for its Physio-pathological Actions

Name: The Influence of Vitamin D on Neurodegeneration and Neurological Disorders: A Rationale for its Physio-pathological Actions
Keywords: amyotrophic lateral sclerosis, Settore BIOS-09/A - Biochimica clinica e biologia molecolare clinica, Multiple Sclerosis, Parkinson's disease, [SDV.MHEP.PSM] Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health, [SDV.NEU.NB] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, 610, Vitamins, Alzheimer's disease, [SDV.BC.IC] Life Sciences [q-bio]/Cellular Biology/Cell Behavior [q-bio.CB]

descriptionPublicationkeyboard_double_arrow_right Article 24 Jun 2020 Italy English Publisher:Bentham Science Publishers Ltd.Journal:Current Pharmaceutical Design, volume 26, pages 2,475-2,491 (issn: 1381-6128,

Authors: Maria Morello; Massimo Pieri; Rossella Zenobi; Alessandra Talamo; Delphine Stephan; Verena Landel; François Féron; +1 Authors

doi: 10.2174/1381612826666200316145725

pmid: 32175837

handle: 2108/266662

The Influence of Vitamin D on Neurodegeneration and Neurological Disorders: A Rationale for its Physio-pathological Actions

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Abstract

Vitamin D is a steroid hormone implicated in the regulation of neuronal integrity and many brain functions. Its influence, as a nutrient and a hormone, on the physiopathology of the most common neurodegenerative diseases is continuously emphasized by new studies. This review addresses what is currently known about the action of vitamin D on the nervous system and neurodegenerative diseases such as Multiple Sclerosis, Alzheimer’s disease, Parkinson’s disease and Amyotrophic Lateral Sclerosis. Further vitamin D research is necessary to understand how the action of this “neuroactive” steroid can help to optimize the prevention and treatment of several neurological diseases.

Country

Italy

Related Organizations

French National Centre for Scientific Research
France
Laboratoire Parole et Langage
France
University of Rome Tor Vergata
Italy
Aix-Marseille University
France
Neurobiology of Cellular Interactions and Neurophysiopathology
France

Keywords

amyotrophic lateral sclerosis, Settore BIOS-09/A - Biochimica clinica e biologia molecolare clinica, Multiple Sclerosis, Parkinson's disease, [SDV.MHEP.PSM] Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health, [SDV.NEU.NB] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, 610, Vitamins, Alzheimer's disease, [SDV.BC.IC] Life Sciences [q-bio]/Cellular Biology/Cell Behavior [q-bio.CB], multiple sclerosis, [SDV.BBM.BM] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, neurodegenerative diseases., [SDV.AEN] Life Sciences [q-bio]/Food and Nutrition, Settore BIO/12 - BIOCHIMICA CLINICA E BIOLOGIA MOLECOLARE CLINICA, Alzheimer Disease, 616, Humans, neurodegenerative diseases, Vitamin D, [SDV.BBM.BC] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM]

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	14
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%