A critical review of U.S. and foreign literature on the use of a mixture of refrigerants rather than a single one in a refrigeration unit indicates that energy can be conserved in properly arranged systems. An independent analytical study performed under the current contract using a 50% mixture of R-12 and R-114 in a two-evaporator refrigerator typical of domestic refrigerators showed an energy saving of 12%. The cycle explored was a non-optimized one, so greater energy savings are theoretically possible. The application of refrigerant mixtures to domestic refrigerators would not be a panacea, but would require a redesign of the refrigeration circuit and a resizing of the compressor. There would be a number of problems to be explored and solved before a successful application could be achieved, but the prospects look favorable at this time. One of the most useful next steps would be to continue to expand the knowledge base on refrigerant mixtures that would be made available to the manufacturers of refrigerators.