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Seibutsu Butsuri
Article . 2010 . Peer-reviewed
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Seibutsu Butsuri
Article
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Network Evolution of Spatial Pattern Formation

Authors: FUJIMOTO, Koichi; ISHIHARA, Shuji; KANEKO, Kunihiko;

Network Evolution of Spatial Pattern Formation

Abstract

One of the major goals in evolutionary developmental biology is to elucidate the relationship between gene regulatory networks and the diverse morphologies. Segmentation in arthropod embryogenesis represents a well-known example of body plan diversity. Striped patterns of gene expression that lead to the future body segments appear simultaneously or sequentially, respectively. To reveal the basic differences in the network structure, we have numerically evolved hundreds of gene regulatory networks. By analyzing the topologies of the generated networks, we show that the characteristics of striped pattern are determined by Feed-Forward Loops (FFLs) and negative Feed-Back Loops (nFBLs).

Keywords

pattern formation, evolutionary developmental biology, segmentation, arthropod, mathematical modeling, gene regulatory network

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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