In previous research endeavours on national economic development, almost no studies exist on how regional confidence can influence its industrial and economic well-being. Therefore, this paper provides a cultural ecology parenthesis, which integrates climatic, geographic, and genetic factors to spell out the forces of confidence on the national economic well-being, which is reflected by the gross national income per capita (GNI). By applying the non-parametric test, the correlation between the mean level of Rosenberg self-esteem scale and GNI per capital growth of 42 countries across the globe will be spelled out to support the cultural ecology parenthesis of confidence on overall economic development.