The analysis of repeated disability of the adult population as a result of diseases of the genitourinary system in Moscow in comparison with the indicators of the Central Federal District and the Russian Federation for the period 2015-2019 revealed that extensive and intensive indicators of repeated disability in Moscow are lower than in the Central Federal District and the Russian Federation. In the age structure of repeated disability among young people as a result of diseases of the genitourinary system, the predominance in the Russian Federation was revealed, significant differences in values and dynamics among young people in Moscow and the Central Federal district were not revealed. The lowest proportion of middle-aged people was recorded in Moscow, which is lower than in the Central Federal district and the Russian Federation. There was a significant predominance of people of retirement age with a tendency to increase their level and share. The severity of disability was dominated by I group of disabled people with a tendency of increasing their specific weight and a relatively stable level. The second place was taken by disabled people of II group with a tendency of increasing their share.