The present work aims to develop a structured exploratory systematic review, based on the results found around the terms "Handball" and "Disability". To carry out the search of the documents, the following keywords were used: "Handball" and "Disability". The documents were searched in the Scopus and Web of Science databases, obtaining a final number of 6 valid documents published prior to September 2021. To adjust the search to the object of study, a series of inclusion and exclusion criteria were established. In the results, it is observed that the most repeated studies are Empirical Studies with Qualitative Methodology about the performance of Wheelchair Handball players. In conclusion, the documents on handball for people with disabilities show that Wheelchair Handball can be beneficial in improving quality of life, functionality, independence, and the acquisition of healthy lifestyles.