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Expert Review of Vaccines
Article . 2010 . Peer-reviewed
Data sources: Crossref
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Vaccines against peste des petits ruminants virus

Authors: Arnab, Sen; Paramasivam, Saravanan; Vinayagamurthy, Balamurugan; Kaushal Kishor, Rajak; Shashi Bhushan, Sudhakar; Veerakyathappa, Bhanuprakash; Satya, Parida; +1 Authors

Vaccines against peste des petits ruminants virus

Abstract

Peste des petits ruminants (PPR) is a highly contagious and economically important viral disease affecting goats, sheep and wild ruminants. The disease is currently circulating in Asian and African countries, creating problems in small ruminant farming. Current control of the disease mainly includes isolation and disinfection of the contaminated environment, and administration of a live-attenuated vaccine, which provides a strong immunity. Maintenance of cold chain for vaccine efficacy has proven difficult in subtropical countries. A thermostable live-attenuated conventional or recombinant vaccine is a way to avoid cold chain-associated problems in tropical and subtropical countries. Mass vaccination of sheep and goats in endemic countries might be a pragmatic approach to control PPR in the first phase of disease eradication. In the future, the development of a marker vaccine with a robust companion test may help in serosurveillance to identify infection in vaccinated animals to control PPR disease. Here, we discuss available potent PPR vaccines and the future possibility of developing new-generation vaccines against PPR.

Keywords

Asia, Goat Diseases, Sheep, Goats, Vaccines, Marker, Temperature, Sheep Diseases, Viral Vaccines, Vaccines, Attenuated, Peste-des-petits-ruminants virus, Refrigeration, Africa, Peste-des-Petits-Ruminants, Animals

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    popularity
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
103
Top 10%
Top 10%
Top 10%
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