Let $x^{(n)}$ denotes the Pochhammer symbol (rising factorial) defined by the formulas $x^{(0)}=1$ and $x^{(n)}=x(x+1)(x+2)\cdots (x+n-1)$ for $n\geq 1$. In this paper, we present a new real-valued Appell-type polynomial family $A_n^{(k)}(m,x)$, $n, m \in {\mathbb{N}}_0$, $k \in {\mathbb{N}},$ every member of which is expressed by mean of the generalized hypergeometric function ${}_{p} F_q \begin{bmatrix} \begin{matrix} a_1, a_2, \ldots, a_p \:\\ b_1, b_2, \ldots, b_q \end{matrix} \: \Bigg| \:z \end{bmatrix}= \sum\limits_{k=0}^{\infty} \frac{a_1^{(k)} a_2^{(k)} \ldots a_p^{(k)}}{b_1^{(k)} b_2^{(k)} \ldots b_q^{(k)}} \frac{z^k}{k!}$ as follows $$ A_n^{(k)}(m,x)= x^n{}_{k+p} F_q \begin{bmatrix} \begin{matrix} {a_1}, {a_2}, {\ldots}, {a_p}, {\displaystyle -\frac{n}{k}}, {\displaystyle -\frac{n-1}{k}}, {\ldots}, {\displaystyle-\frac{n-k+1}{k}}\:\\ {b_1}, {b_2}, {\ldots}, {b_q} \end{matrix} \: \Bigg| \: \displaystyle \frac{m}{x^k} \end{bmatrix} $$ and, at the same time, the polynomials from this family are Appell-type polynomials. The generating exponential function of this type of polynomials is firstly discovered and the proof that they are of Appell-type ones is given. We present the differential operator formal power series representation as well as an explicit formula over the standard basis, and establish a new identity for the generalized hypergeometric function. Besides, we derive the addition, the multiplication and some other formulas for this polynomial family.