This article proposes the idea of a dialogue between Christian apocrypha and early Islam. The discussion shows the role which the Qur’ān as the key text of early Islamic literature played in the transmission of Christian apocrypha in the Byzantine world. The parallel between the Qur’ānic material on Mary’s youth, conception, birth-giving, and Jesus’ childhood and the development of the “Book of Mary” at the stage where Protoevangelium of James and Infancy Gospel of Pseudo-Thomas were being joined to one another suggests that the Qur’ān functions as a witness to a formative period of a Christian apocryphal text.