Environmental problems were initiated with the rise of human civilization, and they increased with the rise in technology’s contribution to human lives. Researchers in the field of architecture believe that regenerative approaches are systems based on aligning architectural design with natural resources to provide positive outcomes. Regenerative design holds significant promise for a new theory of sustainable architecture. The aim of this paper is to provide a theoretical framework for the concept of regenerative architecture and testing materials’ effectiveness (thermal, availability, waste, and toxicity) and impacts on shifting towards regenerative architecture. Materials’ thermal properties were examined by determining energy consumption through Ecotect as a simulation program. However, other factors were measured by a checklist derived from an intense review of the literature. The results revealed that the existing current buildings in Erbil City do not lie in the regenerative zone. Moreover, the study also shows that material selection plays a significant role in reducing energy consumption and toxicity levels that result from moving architectural design towards regenerative design.