In this report we evaluate potential tsunami hazards for the southeastern Alaska community of Yakutat and numerically model the extent of inundation from tsunami waves generated by tectonic and landslide sources. We use numerical modeling of historical tsunami events at Yakutat, such as the tsunami triggered by the 1964 Great Alaska Earthquake, and the tsunami waves generated by the recent 2011 Tohoku earthquake, to verify the tsunami model. Potential hypothetical tsunami sources include variations of the extended 1964 rupture, megathrust earthquakes in the Prince William Sound and Alaska Peninsula regions, and earthquakes in the Yakataga-Yakutat area, including the historical September 10, 1899, earthquake. Local underwater landslide events in Monti Bay are also considered as possible tsunamigenic scenarios. Numerical modeling results, combined with historical observations in the region, are intended to provide guidance to local emergency management in tsunami hazard assessment, evacuation planning, and public education for the reduction of future tsunami hazard.