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Potential distributions of Bacillus anthracis and Bacillus cereus biovar anthracis causing anthrax in Africa

Authors: Lindsay P. Campbell; Claudia Pittiglio; Daniel Romero-Alvarez; Johanna S. Salzer; William A. Bower; A. Townsend Peterson; Henry Walke; +4 Authors

Potential distributions of Bacillus anthracis and Bacillus cereus biovar anthracis causing anthrax in Africa

Abstract

(Uploaded by Plazi for the Bat Literature Project) Bacillus cereus biovar anthracis (Bcbva) is an emergent pathogen causing anthrax in West and Central African countries. It shares multiple bacteriological and genomic characteristics with Bacillus anthracis, the gram-positive bacterium causing anthrax in mammals worldwide. However, Bcbva has only been isolated in tropical humid forested environments in Africa; thus, we attempted to characterize its potential distribution and the differences with B. anthracis using an ecological niche modeling framework. According to our results, both pathogens are using different environments and their distribution looks complementary with B. anthracis occupying savanna-like environments and Bcbva occupying forested areas; further, we detected some level of overlap between the potential geographic distributions of B. anthracis and Bcbva, despite their lack of overlap in their current environmental space. This is the first time the potential distribution of Bcbva is addressed considering all the available spatial information on the pathogen occurrence available as of 2017. Although our Bcbva models are limited due to sample size, this exploration informs on areas that would likely be considered for further investigation of Bcbva outbreaks with special emphasis on areas where Bcbva and B. anthracis could co-exist.

Keywords

RC955-962, bats, bat, 630, Anthrax, Bacillus cereus, Arctic medicine. Tropical medicine, Chiroptera, Animals, Humans, Animalia, Chordata, Models, Statistical, 600, Biodiversity, Phylogeography, Bacillus anthracis, Africa, Mammalia, Topography, Medical, Public aspects of medicine, RA1-1270, Research Article

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    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    42
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
42
Top 10%
Top 10%
Top 10%
Green
gold