Alkaloids from the South China Sea Black Coral Antipathes dichotoma
Copyright policy )Alkaloids from the South China Sea Black Coral Antipathes dichotoma
A new carbazole alkaloid, antipathine A (1), together with three known zoanthoxanthin alkaloids (2--4) was isolated from the EtOH/CH2Cl2 extracts of the South China Sea black coral Antipathes dichotoma. The structure of 1 was determined on the bases of extensive spectroscopic analysis, including 1D and 2D NMR data. Compounds 1 and 2 showed moderate cytotoxicity against human stomach carcinoma SGC-7901 cell line with IC50 of 67.38 and 86.40 microg/ml, respectively, and 1 and 2 also showed weak cytotoxicity toward human liver carcinoma Hep_G2 cell line.
- South China Sea Institute Of Oceanology China (People's Republic of)
- Chinese Academy of Sciences China (People's Republic of)
China, Molecular Structure, Oceans and Seas, Liver Neoplasms, Antineoplastic Agents, Anthozoa, Inhibitory Concentration 50, Alkaloids, Stomach Neoplasms, Cell Line, Tumor, Animals, Humans, Drug Screening Assays, Antitumor, Nuclear Magnetic Resonance, Biomolecular
China, Molecular Structure, Oceans and Seas, Liver Neoplasms, Antineoplastic Agents, Anthozoa, Inhibitory Concentration 50, Alkaloids, Stomach Neoplasms, Cell Line, Tumor, Animals, Humans, Drug Screening Assays, Antitumor, Nuclear Magnetic Resonance, Biomolecular
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