
doi: 10.1248/cpb.40.2647
Following the chemical characterization of calotroposides A (1) and B (2), five related oxypregnane-oligoglycosides named calotroposides C (3), D (4), E (5), F (6), and G (7) have benn additionally isolated from the root of Calotropis gigantea (Asclepiadaceae), an Indonesian medicinal plant. The chemical structures of the new calotroposides have been elucidated on the basis of chemical and physicochemical properties as 12-O-benzoyldeacetylmetaplexigenin 3-O-β-D-oleandropyranosyl(1→4)-β-D-oleandropyranosyl(1→4)-β-D-oleandropyranosyl(1→4)-β-D-cymaropyranosyl(1→4)-β-D-cymaropyranoside for 3, 12-O-benzoyllineolon 3-O-β-D-oleandropyranosyl(1→4)-β-D-oleandropyranosyl(1→4)-β-D-oleandropyranosyl(1→4)-β-D-cymaropyranosyl(1→4)-β-D-cymaropyranoside for 4, 12-O-benzoyldeacetylmetaplexigenin 3-O-β-D-oleandropyranosyl(1→4)-β-D-oleandropyranosyl(1→4)-β-D-cymaropyranosyl(1→4)-β-D-cymaropyranoside for 5, 12-O-benzoyllineolon 3-O-β-D-oleandropyranosyl(1→4)-β-D-oleandropyranosyl(1→4)-β-D-cymaropyranosyl(1→4)-β-D-cymaropyranoside for 6, and 12-O-benzoyllineolon 3-O-β-D-oleandropyranosyl(1→4)-β-D-cymaropyranosyl(1→4)-β-D-cymaropyranoside for 7.
Asclepiadaceae, calotroposide, Calotropis gigantea, cymarose, oleandrose, oxypregnane-oligoglycoside, Indonesian medicinal plant
Asclepiadaceae, calotroposide, Calotropis gigantea, cymarose, oleandrose, oxypregnane-oligoglycoside, Indonesian medicinal plant
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