Potent Antihepatotoxic Activity of Dicaffeoyl Quinic Acids from Propolis.
Copyright policy )Potent Antihepatotoxic Activity of Dicaffeoyl Quinic Acids from Propolis.
Hepatoprotective activity guided chemical analyses led to the isolation of two dicaffeoyl quinic acid derivatives, methyl 3,4-di-O-caffeoyl quinate (1) and 3,4-di-O-caffeoyl quinic acid (2) from water extract of propolis, and their structures were determined by the use of 2D NMR. These compounds were stronger antihepatotoxic agents than glycyrrhizin.
- University of Toyama Japan
Magnetic Resonance Spectroscopy, L-Lactate Dehydrogenase, Molecular Structure, Liver Diseases, Quinic Acid, Alanine Transaminase, Glycyrrhizic Acid, Mass Spectrometry, Propolis, Rats, Disease Models, Animal, Liver, Animals, Glycyrrhetinic Acid, Aspartate Aminotransferases, Chemical and Drug Induced Liver Injury, Carbon Tetrachloride, Cells, Cultured
Magnetic Resonance Spectroscopy, L-Lactate Dehydrogenase, Molecular Structure, Liver Diseases, Quinic Acid, Alanine Transaminase, Glycyrrhizic Acid, Mass Spectrometry, Propolis, Rats, Disease Models, Animal, Liver, Animals, Glycyrrhetinic Acid, Aspartate Aminotransferases, Chemical and Drug Induced Liver Injury, Carbon Tetrachloride, Cells, Cultured
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