ABSTRACT The regeneration of limbs, after simple amputation, in two families (four genera) of primitive anurans was investigated. All produced hypotypic regenerates of varying size and degree of morphogenesis. Despite certain differences possibly related to phylogenetic affinities, both Discoglossidae and Pipidae regenerated in similar fashion. Regenerates consisted chiefly of well-developed rods of cartilage, surrounded by connective tissue and skin. Muscle regeneration was minimal, resulting in the formation of small striated slips. The role of the stump tissues and their possible relation to the development of the hypotypic regenerate was discussed.