Half-way between molecular and materials chemistries lies the field of colloidal chemistry where the shape, the size, and the morphology of supramolecular assemblies are key parameters that determine their intrinsic properties, such as their interfacial behavior, surface chemistry, density, and so on. In this review, we aim to gather some of the most significant works carried out within the last few years and dealing with particles wherein the spatial distribution of these properties is not isotropic. Therefore, we present some interesting synthetic routes suggested by researchers all around the world and leading to dumbbell-like, snowman-like or Janus-like nanoparticles whose potential remarkable properties are also discussed.