In this paper, elaboration of a Realist answer to some of the classical questions of psychology and epistemology will be sought, starting from a knowledge of Soviet and Western findings in psychophysiology (particularly the work of Pavlov, 1932, and Hebb, 1949; see also the summary by Burt, 1968). The point of departure taken in the philosophical literature is the paper by Place (1969). This paper will adopt a reflexological model of brain function—with its implied view that memory is synaptically encoded. While this model has largely fallen into disfavour it is used here paradigmatically—to show that well-developed physiological models in general can provide a satisfactory account of ‘mental’ phenomena.