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High prevalence of myeloid neoplasms in adults with non–Langerhans cell histiocytosis

Authors: Papo, Matthias; Diamond, Eli; Cohen-Aubart, Fleur; Emile, Jean-François; Roos-Weil, Damien; Gupta, Nishant; Durham, Benjamin; +16 Authors

High prevalence of myeloid neoplasms in adults with non–Langerhans cell histiocytosis

Abstract

Key Points Some 10.1% of adults with non–Langerhans cell histiocytosis have a concomitant myeloid neoplasm with each often harboring distinct mutations. The presence of distinct kinase mutations in histiocytosis and myeloid neoplasms resulted in discordant responses to targeted therapy.

Country
France
Keywords

Adult, Male, Erdheim-Chester Disease, Histiocytosis, Non-Langerhans-Cell, [SDV]Life Sciences [q-bio], 610, Middle Aged, [SDV] Life Sciences [q-bio], Prevalence, Humans, Female, Molecular Targeted Therapy, Bone Marrow Neoplasms, Aged

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    117
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 1%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
117
Top 1%
Top 10%
Top 1%
bronze